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An Enantioselective Cross Dehydrogenative Coupling Catalysis Approach to Substituted Tetrahydropyrans

An enantioselective cross-dehydrogenative coupling (CDC) reaction to access tetrahydropyrans has been developed. This process combines in situ Lewis acid activation of a nucleophile in concert with the oxidative formation of a transient oxocarbenium electrophile, leading to a productive and highly e...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Lee, Ansoo, Betori, Rick C., Crane, Erika A., Scheidt, Karl A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052785/
https://ncbi.nlm.nih.gov/pubmed/29714480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b03063
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