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A Cooperative Hydrogen Bond Donor/Brønsted Acid System for the Enantioselective Synthesis of Tetrahydropyrans

Carbocations stabilized by adjacent oxygen atoms are useful reactive intermediates involved in fundamental chemical transformations. These oxocarbenium ions typically lack sufficient electron density to engage established chiral Brønsted or Lewis acid catalysts, presenting a major challenge to their...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Maskeri, Mark A., O’Connor, Matthew J., Jaworski, Ashley A., Davies, Anna V., Scheidt, Karl A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6419772/
https://ncbi.nlm.nih.gov/pubmed/30380196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201811383
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