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Inhibition of protein arginine methyltransferase 5 enhances hepatic mitochondrial biogenesis

Protein arginine methyltransferase 5 (PRMT5) regulates gene expression either transcriptionally by symmetric dimethylation of arginine residues on histones H4R3, H3R8, and H2AR3 or at the posttranslational level by methylation of nonhistone target proteins. Although emerging evidence suggests that P...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Huang, Lei, Liu, Jehnan, Zhang, Xiao-Ou, Sibley, Katelyn, Najjar, Sonia M., Lee, Mary M., Wu, Qiong
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052201/
https://ncbi.nlm.nih.gov/pubmed/29773653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002377
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