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Inhibition of protein arginine methyltransferase 5 enhances hepatic mitochondrial biogenesis

Protein arginine methyltransferase 5 (PRMT5) regulates gene expression either transcriptionally by symmetric dimethylation of arginine residues on histones H4R3, H3R8, and H2AR3 or at the posttranslational level by methylation of nonhistone target proteins. Although emerging evidence suggests that P...

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Vydáno v:J Biol Chem
Hlavní autoři: Huang, Lei, Liu, Jehnan, Zhang, Xiao-Ou, Sibley, Katelyn, Najjar, Sonia M., Lee, Mary M., Wu, Qiong
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052201/
https://ncbi.nlm.nih.gov/pubmed/29773653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002377
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