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Crystal structure and substrate binding mode of ectonucleotide phosphodiesterase/pyrophosphatase-3 (NPP3)

Ectonucleotide phosphodiesterase/pyrophosphatase-3 (NPP3) is a membrane-bound glycoprotein that regulates extracellular levels of nucleotides. NPP3 is known to contribute to the immune response on basophils by hydrolyzing ATP and to regulate the glycosyltransferase activity in Neuro2a cells. Here, w...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Döhler, Christoph, Zebisch, Matthias, Sträter, Norbert
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052110/
https://ncbi.nlm.nih.gov/pubmed/30022031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28814-y
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