Renoprotective effects of a factor Xa inhibitor: fusion of basic research and a database analysis

Renal tubulointerstitial injury, an inflammation-associated condition, is a major cause of chronic kidney disease (CKD). Levels of activated factor X (FXa), a blood coagulation factor, are increased in various inflammatory diseases. Therefore, we investigated the protective effects of an FXa inhibit...

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Udgivet i:Sci Rep
Main Authors: Horinouchi, Yuya, Ikeda, Yasumasa, Fukushima, Keijo, Imanishi, Masaki, Hamano, Hirofumi, Izawa-Ishizawa, Yuki, Zamami, Yoshito, Takechi, Kenshi, Miyamoto, Licht, Fujino, Hiromichi, Ishizawa, Keisuke, Tsuchiya, Koichiro, Tamaki, Toshiaki
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052035/
https://ncbi.nlm.nih.gov/pubmed/30022146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29008-2
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