Iron Chelation by Deferoxamine Prevents Renal Interstitial Fibrosis in Mice with Unilateral Ureteral Obstruction

Renal fibrosis plays an important role in the onset and progression of chronic kidney diseases (CKD). Although several mechanisms underlying renal fibrosis and candidate drugs for its treatment have been identified, the effect of iron chelator on renal fibrosis remains unclear. In the present study,...

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Main Authors: Ikeda, Yasumasa, Ozono, Iori, Tajima, Soichiro, Imao, Mizuki, Horinouchi, Yuya, Izawa-Ishizawa, Yuki, Kihira, Yoshitaka, Miyamoto, Licht, Ishizawa, Keisuke, Tsuchiya, Koichiro, Tamaki, Toshiaki
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929716/
https://ncbi.nlm.nih.gov/pubmed/24586712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089355
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