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Iron Chelation by Deferoxamine Prevents Renal Interstitial Fibrosis in Mice with Unilateral Ureteral Obstruction

Renal fibrosis plays an important role in the onset and progression of chronic kidney diseases (CKD). Although several mechanisms underlying renal fibrosis and candidate drugs for its treatment have been identified, the effect of iron chelator on renal fibrosis remains unclear. In the present study,...

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書誌詳細
主要な著者: Ikeda, Yasumasa, Ozono, Iori, Tajima, Soichiro, Imao, Mizuki, Horinouchi, Yuya, Izawa-Ishizawa, Yuki, Kihira, Yoshitaka, Miyamoto, Licht, Ishizawa, Keisuke, Tsuchiya, Koichiro, Tamaki, Toshiaki
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929716/
https://ncbi.nlm.nih.gov/pubmed/24586712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089355
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