Array comparative genomic hybridization identifies high level of PI3K/Akt/mTOR pathway alterations in anal cancer recurrences

Genomic alterations of anal squamous cell carcinoma (ASCC) remain poorly understood due to the rarity of this tumor. Array comparative genomic hybridization and targeted gene sequencing were performed in 49 cases of ASCC. The most frequently altered regions (with a frequency greater than 25%) were 1...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Cacheux, Wulfran, Tsantoulis, Petros, Briaux, Adrien, Vacher, Sophie, Mariani, Pascale, Richard‐Molard, Marion, Buecher, Bruno, Richon, Sophie, Jeannot, Emmanuelle, Lazartigues, Julien, Rouleau, Etienne, Mariani, Odette, El Alam, Elsy, Cros, Jérôme, Roman‐Roman, Sergio, Mitry, Emmanuel, Girard, Elodie, Dangles‐Marie, Virginie, Lièvre, Astrid, Bièche, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6051172/
https://ncbi.nlm.nih.gov/pubmed/29804324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1533
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