Structure-Function Analysis of the Curli Accessory Protein CsgE Defines Surfaces Essential for Coordinating Amyloid Fiber Formation

Curli amyloid fibers are produced as part of the extracellular biofilm matrix and are composed primarily of the major structural subunit CsgA. The CsgE chaperone facilitates the secretion of CsgA through CsgG by forming a cap at the base of the nonameric CsgG outer membrane pore. We elucidated a ser...

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Udgivet i:mBio
Main Authors: Klein, Roger D., Shu, Qin, Cusumano, Zachary T., Nagamatsu, Kanna, Gualberto, Nathaniel C., Lynch, Aaron J. L., Wu, Chao, Wang, Wenjie, Jain, Neha, Pinkner, Jerome S., Amarasinghe, Gaya K., Hultgren, Scott J., Frieden, Carl, Chapman, Matthew R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050966/
https://ncbi.nlm.nih.gov/pubmed/30018113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01349-18
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