Structure-Function Analysis of the Curli Accessory Protein CsgE Defines Surfaces Essential for Coordinating Amyloid Fiber Formation

Curli amyloid fibers are produced as part of the extracellular biofilm matrix and are composed primarily of the major structural subunit CsgA. The CsgE chaperone facilitates the secretion of CsgA through CsgG by forming a cap at the base of the nonameric CsgG outer membrane pore. We elucidated a ser...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Klein, Roger D., Shu, Qin, Cusumano, Zachary T., Nagamatsu, Kanna, Gualberto, Nathaniel C., Lynch, Aaron J. L., Wu, Chao, Wang, Wenjie, Jain, Neha, Pinkner, Jerome S., Amarasinghe, Gaya K., Hultgren, Scott J., Frieden, Carl, Chapman, Matthew R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050966/
https://ncbi.nlm.nih.gov/pubmed/30018113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01349-18
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