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The Main Role of Srs2 in DNA Repair Depends on Its Helicase Activity, Rather than on Its Interactions with PCNA or Rad51

Homologous recombination (HR) is a mechanism that repairs a variety of DNA lesions. Under certain circumstances, however, HR can generate intermediates that can interfere with other cellular processes such as DNA transcription or replication. Cells have therefore developed pathways that abolish unde...

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Pubblicato in:mBio
Autori principali: Bronstein, Alex, Gershon, Lihi, Grinberg, Gilad, Alonso-Perez, Elisa, Kupiec, Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050964/
https://ncbi.nlm.nih.gov/pubmed/30018112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01192-18
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