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IL-10 Receptor Signaling Empowers Regulatory T Cells to Control Th17 Responses and Protect from GN
Background Th17 cells are central pathogenic mediators of autoimmune disease, including many forms of GN. IL-10 receptor signaling (IL-10R) in regulatory T cells (Tregs) has been implicated in the downregulation of Th17 cells, but the underlying molecular mechanisms and functional relevance of this...
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| Publicado no: | J Am Soc Nephrol |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Nephrology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6050938/ https://ncbi.nlm.nih.gov/pubmed/29866800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017091044 |
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