The Calcium-Sensing Receptor Increases Activity of the Renal NCC through the WNK4-SPAK Pathway

Background Hypercalciuria can result from activation of the basolateral calcium-sensing receptor (CaSR), which in the thick ascending limb of Henle’s loop controls Ca(2+) excretion and NaCl reabsorption in response to extracellular Ca(2+). However, the function of CaSR in the regulation of NaCl reab...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Bazúa-Valenti, Silvana, Rojas-Vega, Lorena, Castañeda-Bueno, María, Barrera-Chimal, Jonatan, Bautista, Rocío, Cervantes-Pérez, Luz G., Vázquez, Norma, Plata, Consuelo, Murillo-de-Ozores, Adrián R., González-Mariscal, Lorenza, Ellison, David H., Riccardi, Daniela, Bobadilla, Norma A., Gamba, Gerardo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2018
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050918/
https://ncbi.nlm.nih.gov/pubmed/29848507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017111155
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