DNA methylation changes in CD4(+) T cells isolated from multiple sclerosis patients on dimethyl fumarate

BACKGROUND: Dimethyl fumarate is an oral treatment for multiple sclerosis, whose mechanism of action is not fully understood. OBJECTIVE: To investigate the effects of dimethyl fumarate on DNA methylation in the CD4(+) T cells of multiple sclerosis patients. METHODS: We performed Illumina EPIC arrays...

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Vydáno v:Mult Scler J Exp Transl Clin
Hlavní autoři: Maltby, Vicki E, Lea, Rodney A, Ribbons, Karen A, Sanders, Katherine A, Kennedy, Daniel, Min, Myintzu, Scott, Rodney J, Lechner-Scott, Jeannette
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2018
Témata:
Short Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050818/
https://ncbi.nlm.nih.gov/pubmed/30038789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2055217318787826
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