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Differential methylation at MHC in CD4(+) T cells is associated with multiple sclerosis independently of HLA-DRB1
BACKGROUND: Although many genetic variants have been associated with multiple sclerosis (MS) risk, they do not explain all the disease risk and there remains uncertainty as to how these variants contribute to disease. DNA methylation is an epigenetic mechanism that can influence gene expression and...
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| Publicado no: | Clin Epigenetics |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5516341/ https://ncbi.nlm.nih.gov/pubmed/28729889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-017-0371-1 |
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