Next-generation sequencing reveals broad down-regulation of microRNAs in secondary progressive multiple sclerosis CD4+ T cells

BACKGROUND: Immunoactivation is less evident in secondary progressive MS (SPMS) compared to relapsing-remitting disease. MicroRNA (miRNA) expression is integral to the regulation of gene expression; determining their impact on immune-related cell functions, especially CD4+ T cells, during disease pr...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Sanders, Katherine A., Benton, Miles C., Lea, Rod A., Maltby, Vicki E., Agland, Susan, Griffin, Nathan, Scott, Rodney J., Tajouri, Lotti, Lechner-Scott, Jeannette
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5002332/
https://ncbi.nlm.nih.gov/pubmed/27570566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0253-y
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