Longitudinal structural cerebral changes related to core CSF biomarkers in preclinical Alzheimer's disease: A study of two independent datasets

Alzheimer's disease (AD) is characterized by an accumulation of β-amyloid (Aβ(42)) accompanied by brain atrophy and cognitive decline. Several recent studies have shown that Aβ(42) accumulation is associated with gray matter (GM) changes prior to the development of cognitive impairment, in the...

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Publicado en:Neuroimage Clin
Autores principales: Falcon, Carles, Tucholka, Alan, Monté-Rubio, Gemma C., Cacciaglia, Raffaele, Operto, Grégory, Rami, Lorena, Gispert, Juan Domingo, Molinuevo, José Luis
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2018
Materias:
Regular Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050455/
https://ncbi.nlm.nih.gov/pubmed/30023169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2018.04.016
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