Longitudinal structural cerebral changes related to core CSF biomarkers in preclinical Alzheimer's disease: A study of two independent datasets

Alzheimer's disease (AD) is characterized by an accumulation of β-amyloid (Aβ(42)) accompanied by brain atrophy and cognitive decline. Several recent studies have shown that Aβ(42) accumulation is associated with gray matter (GM) changes prior to the development of cognitive impairment, in the...

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Detalhes bibliográficos
Publicado no:Neuroimage Clin
Main Authors: Falcon, Carles, Tucholka, Alan, Monté-Rubio, Gemma C., Cacciaglia, Raffaele, Operto, Grégory, Rami, Lorena, Gispert, Juan Domingo, Molinuevo, José Luis
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050455/
https://ncbi.nlm.nih.gov/pubmed/30023169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2018.04.016
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