Development of nsP2 protease based cell free high throughput screening assay for evaluation of inhibitors against emerging Chikungunya virus

Chikungunya virus has emerged as one of the most important global arboviral threats over the last decade. Inspite of large scale morbidity, with long lasting polyarthralgia, so far no licensed vaccine or antiviral is available. CHIKV nsP2 protease is crucial for processing of viral nonstructural pol...

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Udgivet i:Sci Rep
Main Authors: Saha, Amrita, Acharya, Badri Narayan, Priya, Raj, Tripathi, Nagesh K., Shrivastava, Ambuj, Rao, M. Kameswara, Kesari, Pooja, Narwal, Manju, Tomar, Shailly, Bhagyawant, Sameer S., Parida, Manmohan, Dash, Paban Kumar
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050329/
https://ncbi.nlm.nih.gov/pubmed/30018455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29024-2
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