APOE DNA methylation is altered in Lewy body dementia

INTRODUCTION: Inheritance of the ε4 allele of apolipoprotein E (APOE) increases a person’s risk of developing both Alzheimer’s disease (AD) and Lewy body dementia (LBD), yet the underlying mechanisms behind this risk are incompletely understood. The recent identification of reduced APOE DNA methylat...

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Vydáno v:Alzheimers Dement
Hlavní autoři: Tulloch, Jessica, Leong, Lesley, Chen, Sunny, Keene, C. Dirk, Millard, Steven P., Shutes-David, Andrew, Lopez, Oscar L., Kofler, Julia, Kaye, Jeffrey A., Woltjer, Randy, Nelson, Peter T., Neltner, Janna H., Jicha, Gregory A., Galasko, Douglas, Masliah, Eliezer, Leverenz, James B., Yu, Chang-En, Tsuang, Debby
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050144/
https://ncbi.nlm.nih.gov/pubmed/29544979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2018.02.005
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