GBA mutations increase risk for Lewy body disease with and without Alzheimer disease pathology

OBJECTIVES: Mutations in the GBA gene occur in 7% of patients with Parkinson disease (PD) and are a well-established susceptibility factor for PD, which is characterized by Lewy body disease (LBD) neuropathologic changes (LBDNCs). We sought to determine whether GBA influences risk of dementia with L...

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Egile Nagusiak: Tsuang, Debby, Leverenz, James B., Lopez, Oscar L., Hamilton, Ronald L., Bennett, David A., Schneider, Julie A., Buchman, Aron S., Larson, Eric B., Crane, Paul K., Kaye, Jeffrey A., Kramer, Patricia, Woltjer, Randy, Kukull, Walter, Nelson, Peter T., Jicha, Gregory A., Neltner, Janna H., Galasko, Doug, Masliah, Eliezer, Trojanowski, John Q., Schellenberg, Gerard D., Yearout, Dora, Huston, Haley, Fritts-Penniman, Allison, Mata, Ignacio F., Wan, Jia Y., Edwards, Karen L., Montine, Thomas J., Zabetian, Cyrus P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Lippincott Williams & Wilkins 2012
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Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484986/
https://ncbi.nlm.nih.gov/pubmed/23035075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3182735e9a
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