GBA variants are associated with a distinct pattern of cognitive deficits in Parkinson disease

BACKGROUND: Loss-of-function mutations in the GBA gene are associated with more severe cognitive impairment in PD, but the nature of these deficits is not well understood and whether common GBA polymorphisms influence cognitive performance in PD is not yet known. OBJECTIVES/METHODS: We screened the...

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Detalhes bibliográficos
Publicado no:Mov Disord
Main Authors: Mata, Ignacio F., Leverenz, James B., Weintraub, Daniel, Trojanowski, John Q., Chen-Plotkin, Alice, Van Deerlin, Vivianna M., Ritz, Beate, Rausch, Rebecca, Factor, Stewart A., Wood-Siverio, Cathy, Quinn, Joseph F., Chung, Kathryn A., Peterson-Hiller, Amie L., Goldman, Jennifer G., Stebbins, Glenn T., Bernard, Bryan, Espay, Alberto J., Revilla, Fredy J., Devoto, Johnna, Rosenthal, Liana S., Dawson, Ted M., Albert, Marilyn S., Tsuang, Debby, Huston, Haley, Yearout, Dora, Hu, Shu-Ching, Cholerton, Brenna A., Montine, Thomas J., Edwards, Karen L., Zabetian, Cyrus P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724255/
https://ncbi.nlm.nih.gov/pubmed/26296077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.26359
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