GBA variants are associated with a distinct pattern of cognitive deficits in Parkinson disease

BACKGROUND: Loss-of-function mutations in the GBA gene are associated with more severe cognitive impairment in PD, but the nature of these deficits is not well understood and whether common GBA polymorphisms influence cognitive performance in PD is not yet known. OBJECTIVES/METHODS: We screened the...

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Dades bibliogràfiques
Publicat a:Mov Disord
Autors principals: Mata, Ignacio F., Leverenz, James B., Weintraub, Daniel, Trojanowski, John Q., Chen-Plotkin, Alice, Van Deerlin, Vivianna M., Ritz, Beate, Rausch, Rebecca, Factor, Stewart A., Wood-Siverio, Cathy, Quinn, Joseph F., Chung, Kathryn A., Peterson-Hiller, Amie L., Goldman, Jennifer G., Stebbins, Glenn T., Bernard, Bryan, Espay, Alberto J., Revilla, Fredy J., Devoto, Johnna, Rosenthal, Liana S., Dawson, Ted M., Albert, Marilyn S., Tsuang, Debby, Huston, Haley, Yearout, Dora, Hu, Shu-Ching, Cholerton, Brenna A., Montine, Thomas J., Edwards, Karen L., Zabetian, Cyrus P.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724255/
https://ncbi.nlm.nih.gov/pubmed/26296077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.26359
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