APOE ε4 Increases Risk for Dementia in Pure Synucleinopathies

OBJECTIVE: To test for an association between the apolipoprotein E (APOE) ε4 allele and dementias with synucleinopathy. DESIGN: Genetic case-control association study. SETTING: Academic research. PATIENTS: Autopsied subjects were classified into 5 categories: dementia with high-level Alzheimer disea...

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Main Authors: Tsuang, Debby, Leverenz, James B., Lopez, Oscar L., Hamilton, Ronald L., Bennett, David A., Schneider, Julie A., Buchman, Aron S., Larson, Eric B., Crane, Paul K., Kaye, Jeffrey A., Kramer, Patricia, Woltjer, Randy, Trojanowski, John Q., Weintraub, Daniel, Chen-Plotkin, Alice S., Irwin, David J., Rick, Jacqueline, Schellenberg, Gerard D., Watson, G. Stennis, Kukull, Walter, Nelson, Peter T., Jicha, Gregory A., Neltner, Janna H., Galasko, Doug, Masliah, Eliezer, Quinn, Joseph F., Chung, Kathryn A., Yearout, Dora, Mata, Ignacio F., Wan, Jia Y., Edwards, Karen L., Montine, Thomas J., Zabetian, Cyrus P.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580799/
https://ncbi.nlm.nih.gov/pubmed/23407718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2013.600
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