COBRAme: A computational framework for genome-scale models of metabolism and gene expression

Genome-scale models of metabolism and macromolecular expression (ME-models) explicitly compute the optimal proteome composition of a growing cell. ME-models expand upon the well-established genome-scale models of metabolism (M-models), and they enable a new fundamental understanding of cellular grow...

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Bibliographic Details
Published in:PLoS Comput Biol
Main Authors: Lloyd, Colton J., Ebrahim, Ali, Yang, Laurence, King, Zachary A., Catoiu, Edward, O’Brien, Edward J., Liu, Joanne K., Palsson, Bernhard O.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6049947/
https://ncbi.nlm.nih.gov/pubmed/29975681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006302
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