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Computation of condition-dependent proteome allocation reveals variability in the macro and micro nutrient requirements for growth

Sustaining a robust metabolic network requires a balanced and fully functioning proteome. In addition to amino acids, many enzymes require cofactors (coenzymes and engrafted prosthetic groups) to function properly. Extensively validated resource allocation models, such as genome-scale models of meta...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Lloyd, Colton J., Monk, Jonathan, Yang, Laurence, Ebrahim, Ali, Palsson, Bernhard O.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8259983/
https://ncbi.nlm.nih.gov/pubmed/34161321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007817
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