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Computing the functional proteome: recent progress and future prospects for genome-scale models

Constraint-based models enable the computation of feasible, optimal, and realized biological phenotypes from reaction network reconstructions and constraints on their operation. To date, stoichiometric reconstructions have largely focused on metabolism, resulting in genome-scale metabolic models (M-...

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Detalhes bibliográficos
Publicado no:Curr Opin Biotechnol
Main Authors: O’Brien, Edward J., Palsson, Bernhard O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495013/
https://ncbi.nlm.nih.gov/pubmed/25576845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.copbio.2014.12.017
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