Exchange of functional domains between a bacterial conjugative relaxase and the integrase of the human adeno-associated virus

Endonucleases of the HUH family are specialized in processing single-stranded DNA in a variety of evolutionarily highly conserved biological processes related to mobile genetic elements. They share a structurally defined catalytic domain for site-specific nicking and strand-transfer reactions, which...

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Publicado en:PLoS One
Autores principales: Agúndez, Leticia, Zárate-Pérez, Francisco, Meier, Anita F., Bardelli, Martino, Llosa, Matxalen, Escalante, Carlos R., Linden, R. Michael, Henckaerts, Els
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6049929/
https://ncbi.nlm.nih.gov/pubmed/30016371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0200841
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