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Rapid Cue-Specific Remodeling of the Nascent Axonal Proteome

Axonal protein synthesis and degradation are rapidly regulated by extrinsic signals during neural wiring, but the full landscape of proteomic changes remains unknown due to limitations in axon sampling and sensitivity. By combining pulsed stable isotope labeling of amino acids in cell culture with s...

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發表在:Neuron
Main Authors: Cagnetta, Roberta, Frese, Christian K., Shigeoka, Toshiaki, Krijgsveld, Jeroen, Holt, Christine E.
格式: Artigo
語言:Inglês
出版: Cell Press 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048689/
https://ncbi.nlm.nih.gov/pubmed/30008298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.06.004
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