Apoptotic cell-derived extracellular vesicles promote malignancy of glioblastoma via intercellular transfer of splicing factors

Aggressive cancers such as glioblastoma (GBM) contain intermingled apoptotic cells adjacent to proliferating tumor cells. Nonetheless, intercellular signaling between apoptotic and surviving cancer cells remain elusive. In this study, we demonstrate that apoptotic GBM cells paradoxically promote pro...

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Publicado no:Cancer Cell
Main Authors: Pavlyukov, Marat S., Yu, Hai, Bastola, Soniya, Minata, Mutsuko, Shender, Victoria O., Lee, Yeri, Zhang, Suojun, Wang, Jia, Komarova, Svetlana, Wang, Jun, Yamaguchi, Shinobu, Alsheikh, Heba Allah, Shi, Junfeng, Chen, Dongquan, Mohyeldin, Ahmed, Kim, Sung-Hak, Shin, Yong Jae, Anufrieva, Ksenia, Evtushenko, Evgeniy G., Antipova, Nadezhda V., Arapidi, Georgij P., Govorun, Vadim, Pestov, Nikolay B., Shakhparonov, Mikhail I., Lee, L. James, Nam, Do-Hyun, Nakano, Ichiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048596/
https://ncbi.nlm.nih.gov/pubmed/29937354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2018.05.012
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