Apoptotic cell-derived extracellular vesicles promote malignancy of glioblastoma via intercellular transfer of splicing factors

Aggressive cancers such as glioblastoma (GBM) contain intermingled apoptotic cells adjacent to proliferating tumor cells. Nonetheless, intercellular signaling between apoptotic and surviving cancer cells remain elusive. In this study, we demonstrate that apoptotic GBM cells paradoxically promote pro...

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Veröffentlicht in:Cancer Cell
Hauptverfasser: Pavlyukov, Marat S., Yu, Hai, Bastola, Soniya, Minata, Mutsuko, Shender, Victoria O., Lee, Yeri, Zhang, Suojun, Wang, Jia, Komarova, Svetlana, Wang, Jun, Yamaguchi, Shinobu, Alsheikh, Heba Allah, Shi, Junfeng, Chen, Dongquan, Mohyeldin, Ahmed, Kim, Sung-Hak, Shin, Yong Jae, Anufrieva, Ksenia, Evtushenko, Evgeniy G., Antipova, Nadezhda V., Arapidi, Georgij P., Govorun, Vadim, Pestov, Nikolay B., Shakhparonov, Mikhail I., Lee, L. James, Nam, Do-Hyun, Nakano, Ichiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048596/
https://ncbi.nlm.nih.gov/pubmed/29937354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2018.05.012
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