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Mutational and transcriptional landscape of spontaneous gene duplications and deletions in Caenorhabditis elegans

Gene duplication and deletion are pivotal processes shaping the structural and functional repertoire of genomes, with implications for disease, adaptation, and evolution. We employed a mutation accumulation (MA) framework partnered with high-throughput genomics to assess the molecular and transcript...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Konrad, Anke, Flibotte, Stephane, Taylor, Jon, Waterston, Robert H., Moerman, Donald G., Bergthorsson, Ulfar, Katju, Vaishali
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048555/
https://ncbi.nlm.nih.gov/pubmed/29941601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1801930115
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