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Reversible inhibition of the ClpP protease via an N-terminal conformational switch
Protein homeostasis is critically important for cell viability. Key to this process is the refolding of misfolded or aggregated proteins by molecular chaperones or, alternatively, their degradation by proteases. In most prokaryotes and in chloroplasts and mitochondria, protein degradation is perform...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6048506/ https://ncbi.nlm.nih.gov/pubmed/29941580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1805125115 |
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