The Putative De-N-acetylase DnpA Contributes to Intracellular and Biofilm-Associated Persistence of Pseudomonas aeruginosa Exposed to Fluoroquinolones

Persisters are the fraction of antibiotic-exposed bacteria transiently refractory to killing and are recognized as a cause of antibiotic treatment failure. The putative de-N-acetylase DnpA increases persister levels in Pseudomonas aeruginosa upon exposure to fluoroquinolones in broth. In this study...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Khandekar, Shaunak, Liebens, Veerle, Fauvart, Maarten, Tulkens, Paul M., Michiels, Jan, Van Bambeke, Françoise
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048251/
https://ncbi.nlm.nih.gov/pubmed/30042739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.01455
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