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Anionic fluoroquinolones as antibacterials against biofilm-producing Pseudomonas aeruginosa
Pseudomonas aeruginosa is a common biofilm-forming bacterial pathogen implicated in diseases of the lungs. The extracellular polymeric substances (EPS) of respiratory Pseudomonas biofilms are largely comprised of anionic molecules such as rhamnolipids and alginate that promote a mucoid phenotype. In...
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| Publicado no: | Bioorg Med Chem Lett |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4753842/ https://ncbi.nlm.nih.gov/pubmed/26826023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2016.01.012 |
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