The antifungal caspofungin increases fluoroquinolone activity against Staphylococcus aureus biofilms by inhibiting N-acetylglucosamine transferase

Biofilms play a major role in Staphylococcus aureus pathogenicity but respond poorly to antibiotics. Here, we show that the antifungal caspofungin improves the activity of fluoroquinolones (moxifloxacin, delafloxacin) against S. aureus biofilms grown in vitro (96-well plates or catheters) and in viv...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Siala, Wafi, Kucharíková, Soňa, Braem, Annabel, Vleugels, Jef, Tulkens, Paul M, Mingeot-Leclercq, Marie-Paule, Van Dijck, Patrick, Van Bambeke, Françoise
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097165/
https://ncbi.nlm.nih.gov/pubmed/27808087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13286
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