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Serotonin concentration enhancers at clinically relevant doses reduce [(11)C]AZ10419369 binding to the 5-HT(1B) receptors in the nonhuman primate brain
The serotonin (5-HT) system plays an important role in the pathophysiology and treatment of several major psychiatric disorders. Currently, no suitable positron emission tomography (PET) imaging paradigm is available to assess 5-HT release in the living human brain. [(11)C]AZ10419369 binds to 5-HT(1...
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| Gepubliceerd in: | Transl Psychiatry |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group UK
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6048172/ https://ncbi.nlm.nih.gov/pubmed/30013068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-018-0178-7 |
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