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Discovery of a First-in-Class Gut-Restricted RET Kinase Inhibitor as a Clinical Candidate for the Treatment of IBS
[Image: see text] Abdominal pain and abnormal bowel habits represent major symptoms for irritable bowel syndrome (IBS) patients that are not adequately managed. Although the etiology of IBS is not completely understood, many of the functions of the gastrointestinal (GI) tract are regulated by the en...
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| Pubblicato in: | ACS Med Chem Lett |
|---|---|
| Autori principali: | , , , , , , , , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Chemical
Society
2018
|
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6047170/ https://ncbi.nlm.nih.gov/pubmed/30034590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00035 |
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