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Synthesis and Evaluation of a (18)F-Labeled Triazinediamine Analogue for Imaging Mutant IDH1 Expression in Gliomas by PET
[Image: see text] Mutations in the isocitrate dehydrogenase gene 1 (IDH1) are common in gliomas. Studies suggest that IDH1 mutations are early events in glioma formation and are important drivers of malignant progression. Herein, we report the synthesis and evaluation of a (18)F-labeled triazinediam...
Gardado en:
| Publicado en: | ACS Med Chem Lett |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Chemical
Society
2018
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6047021/ https://ncbi.nlm.nih.gov/pubmed/30034587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.7b00478 |
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