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Evaluation of a Janus kinase 1 inhibitor, PF‐04965842, in healthy subjects: A phase 1, randomized, placebo‐controlled, dose‐escalation study
AIMS: To determine the safety, tolerability, pharmacokinetics and pharmacodynamics of the Janus kinase 1‐selective inhibitor, PF‐04965842. METHODS: This was a phase 1, first‐in‐human, randomized, double‐blind, placebo‐controlled, combination single‐ and multiple‐dose escalation, parallel design stud...
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| Pubblicato in: | Br J Clin Pharmacol |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6046510/ https://ncbi.nlm.nih.gov/pubmed/29672897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13612 |
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