A LINE1-Nucleolin partnership regulates early development and ES cell identity

Transposable elements represent nearly half of mammalian genomes and are generally described as parasites or ‘junk DNA’. The LINE1 retrotransposon is the most abundant class and is thought to be deleterious for cells, yet is paradoxically highly expressed during early development. Here we report tha...

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Опубликовано в: :Cell
Главные авторы: Percharde, Michelle, Lin, Chih-Jen, Yin, Yafei, Guan, Juan, Peixoto, Gabriel A., Bulut-Karslioglu, Aydan, Biechele, Steffen, Huang, Bo, Shen, Xiaohua, Ramalho-Santos, Miguel
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6046266/
https://ncbi.nlm.nih.gov/pubmed/29937225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.05.043
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