A LINE1-Nucleolin partnership regulates early development and ES cell identity

Transposable elements represent nearly half of mammalian genomes and are generally described as parasites or ‘junk DNA’. The LINE1 retrotransposon is the most abundant class and is thought to be deleterious for cells, yet is paradoxically highly expressed during early development. Here we report tha...

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Publicat a:Cell
Autors principals: Percharde, Michelle, Lin, Chih-Jen, Yin, Yafei, Guan, Juan, Peixoto, Gabriel A., Bulut-Karslioglu, Aydan, Biechele, Steffen, Huang, Bo, Shen, Xiaohua, Ramalho-Santos, Miguel
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6046266/
https://ncbi.nlm.nih.gov/pubmed/29937225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.05.043
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