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Inactivation of hepatic ATRX in Atrx Foxg1cre mice prevents reversal of aging-like phenotypes by thyroxine

ATRX is an ATP-dependent chromatin remodeler required for the maintenance of genomic integrity. We previously reported that conditional Atrx ablation in the mouse embryonic forebrain and anterior pituitary using the Foxg1cre driver causes reduced health and lifespan. In these mice, premature aging-l...

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Bibliografische gegevens
Gepubliceerd in:Aging (Albany NY)
Hoofdauteurs: Rowland, Megan E., Jiang, Yan, Beier, Frank, Bérubé, Nathalie G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6046231/
https://ncbi.nlm.nih.gov/pubmed/29883366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101462
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