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Loss of ATRX in Chondrocytes Has Minimal Effects on Skeletal Development

BACKGROUND: Mutations in the human ATRX gene cause developmental defects, including skeletal deformities and dwarfism. ATRX encodes a chromatin remodeling protein, however the role of ATRX in skeletal development is currently unknown. METHODOLOGY/PRINCIPAL FINDINGS: We induced Atrx deletion in mouse...

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Detalhes bibliográficos
Main Authors: Solomon, Lauren A., Li, Jennifer R., Bérubé, Nathalie G., Beier, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744333/
https://ncbi.nlm.nih.gov/pubmed/19774083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007106
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