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UTX is an escape from X-inactivation tumor-suppressor in B cell lymphoma

To explain the excess cancer rate in males, several candidates for “escape from X-inactivation tumor-suppressor” (EXITS) were recently identified. In this report we provide direct experimental evidence supporting UTX’s role as an EXITS gene. Using a mouse lymphoma model, we show clear dosage effect...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Li, Xiaoxi, Zhang, Yanli, Zheng, Liting, Liu, Mingxian, Chen, Charlie Degui, Jiang, Hai
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6045675/
https://ncbi.nlm.nih.gov/pubmed/30006524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05084-w
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