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Reconciling Selectivity Trends from a Comprehensive Kinase Inhibitor Profiling Campaign with Known Activity Data
[Image: see text] Kinase inhibitors are among the most intensely investigated compounds in medicinal chemistry and drug development. Profiling experiments and kinome screens reveal binding characteristics of kinase inhibitors and lead to better understanding of selectivity and promiscuity patterns....
Sparad:
| I publikationen: | ACS Omega |
|---|---|
| Huvudupphovsmän: | , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Chemical Society
2018
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| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6045376/ https://ncbi.nlm.nih.gov/pubmed/30023860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b00243 |
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