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New Insights into the Catalytic Mechanism of Aldose Reductase: A QM/MM Study
[Image: see text] Aldose reductase is the first enzyme of the polyol pathway in which glucose is converted to fructose via sorbitol. The understanding of this key enzyme is important as it has been linked to some diabetes mellitus complications. The mechanism of the enzyme was investigated using a h...
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| Опубликовано в: : | ACS Omega |
|---|---|
| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Chemical Society
2017
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| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6044956/ https://ncbi.nlm.nih.gov/pubmed/30023751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b00815 |
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