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Small-Molecule Inhibitors of the NusB–NusE Protein–Protein Interaction with Antibiotic Activity
[Image: see text] The NusB–NusE protein–protein interaction (PPI) is critical to the formation of stable antitermination complexes required for stable RNA transcription in all bacteria. This PPI is an emerging antibacterial drug target. Pharmacophore-based screening of the mini-Maybridge compound li...
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| 發表在: | ACS Omega |
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| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Chemical Society
2017
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| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6044933/ https://ncbi.nlm.nih.gov/pubmed/30023707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b00273 |
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