Small-Molecule Inhibitors of the NusB–NusE Protein–Protein Interaction with Antibiotic Activity

[Image: see text] The NusB–NusE protein–protein interaction (PPI) is critical to the formation of stable antitermination complexes required for stable RNA transcription in all bacteria. This PPI is an emerging antibacterial drug target. Pharmacophore-based screening of the mini-Maybridge compound li...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:ACS Omega
Auteurs principaux: Cossar, Peter J., Abdel-Hamid, Mohammed K., Ma, Cong, Sakoff, Jennette A., Trinh, Trieu N., Gordon, Christopher P., Lewis, Peter J., McCluskey, Adam
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2017
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044933/
https://ncbi.nlm.nih.gov/pubmed/30023707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b00273
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires