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In Silico Screening and Binding Characterization of Small Molecules toward a G-Quadruplex Structure Formed in the Promoter Region of c-MYC Oncogene
[Image: see text] Overexpression of c-MYC oncogene is associated with cancer pathology. Expression of c-MYC is regulated by the G-quadruplex structure formed in the G-rich segment of nuclease hypersensitive element (NHE III(1)), that is, “Pu27”, which is localized in the promoter region. Ligand-indu...
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| Publicado no: | ACS Omega |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2017
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6044917/ https://ncbi.nlm.nih.gov/pubmed/30023722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.6b00531 |
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